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Stephen Orena Selected Research

(3S,3aR)- 2- (3- chloro- 4- cyanophenyl)- 3- cyclopentyl- 3,3a,4,5- tetrahydro- 2H- benzo(g)indazole- 7- carboxylic acid

1/2013PF-03882845, a non-steroidal mineralocorticoid receptor antagonist, prevents renal injury with reduced risk of hyperkalemia in an animal model of nephropathy.

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Stephen Orena Research Topics

Disease

2Malaria
01/2022 - 01/2021
1Neuroblastoma
09/2015
1Fibrosis (Cirrhosis)
01/2013
1Hyperkalemia
01/2013

Drug/Important Bio-Agent (IBA)

1Pyrimethamine (Daraprim)FDA Link
01/2022
1Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA
01/2022
1Proguanil (Paludrine)FDA Link
01/2022
1cycloguanilIBA
01/2022
1ArtemisininsIBA
01/2021
1artemisinin (artemisinine)IBA
01/2021
1Firefly LuciferasesIBA
09/2015
1(3S,3aR)- 2- (3- chloro- 4- cyanophenyl)- 3- cyclopentyl- 3,3a,4,5- tetrahydro- 2H- benzo(g)indazole- 7- carboxylic acidIBA
01/2013
1Eplerenone (Inspra)FDA LinkGeneric
01/2013
1AldosteroneIBA
01/2013
1Mineralocorticoid Receptor AntagonistsIBA
01/2013
1CollagenIBA
01/2013
1salicylhydroxamic acid (SHAM)IBA
01/2013

Therapy/Procedure

1Chemoprevention
01/2022
1Therapeutics
01/2021